The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila

Rommelaere, S., et al. The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila. Cell Reports. 27(3), 886-899.e6. 16/4/2019.

Rommelaere et al. identify a smallexchangeable apolipoprotein inDrosophilathat facilitates dietary lipidextraction and fat storage. Nplp2 sustainslipid flow to fuel the heat stress response,promoting insect survival at elevatedtemperatures. Optimization of lipidtransport during stress via dedicatedlipoproteins likely applies to otherspecies including vertebrates.

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