PEAKS de novo sequencing

Peptide de novo sequencing is essential to every well-executed MS based protein study. If you're not using de novo sequencing regularly, you're missing out:

In a process called de novo sequencing, peptide sequences are derived from the masses of their fragments as shown on a tandem mass spectrum. When performing de novo sequencing, no protein sequence database is used for reference.

One of the cores PEAKS technology is the fastest, most accurate auto de novo algorithm available on the market. Run auto de novo on an entire LC run, or a batch of them - process data faster than you can make it (40+ spectra per second). The results are unmatched in accuracy; PEAKS determines at least 3 times as many completely correct sequences as the next best de novo software. Accurate mass capabilities mean de novo at 97% accuracy is possible.

With its easy to use, easy to read graphical user interface, PEAKS shows reliable and easy to read confidence scores. Confidence is not only on the peptide sequence, but on each amino acid assignment. PEAKS is the only software to provide confidence assignment at the amino acid level. Researchers can find the most pertinent information at a glance. Yet, all the information needed for in depth analysis is provided, without cluttering up the display.

PEAKS can find post-translational modifications on peptides when de novo sequencing, and position them in the sequence.

PEAKS is the only de novo sequencing software specifically tuned to handle data from QTOF, TOF-TOF, Ion Trap, Orbi-Trap and FTMS instruments, while using y and b ions or c and z ions for fragmentation flexibility. It provides a reliable central processing tool for all instrument and experiment types. It is comfortable in any dynamic core facility or demanding private research group.

But PEAKS doesn't stop at auto de novo. In addition to automatic de novo sequencing, PEAKS' comprehensive set of assisted manual sequencing tools allow users to edit the results from a PEAKS processed spectrum. But most importantly, PEAKS has an integrated database search for protein identification tool -- a unique approach to protein ID that uses de novo sequencing to help in the search.

Next Page => Learn about the next generation hybrid and meta-search protein ID tools.

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De Novo Sequencing Protein ID PTM Seq. Tag Search Raw Data Tech Support Request Prices Try PEAKS Our Research User Comments	Superior de novo sequencing and protein ID Software PEAKS De Novo Sequencing Peptide de novo sequencing is essential to every well-executed MS based protein study. If you're not using de novo sequencing regularly, you're missing out: Good quality spectra are often left unexplained after database searching; de novo sequencing is the only recourse. Since a database search cannot reliably find peptides that are unexpectedly modified, de novo sequence information is a valuable first step in finding these PTM. A de novo sequencing based approach is proven to be the best method database search results validation. False positives are virtually eliminated. Sequence tag searching requires good quality de novo sequences to be effective. Coverage can be drastically increased by using a sequence tag based and ms/ms ion searches together. An incomplete or corrupted database is a common, but invisible problem in protein identification and characterization research. How many peptides are you missing because of this? De novo sequencing as a regular part of your workflow will help catch these. When studying species that are not in the public databases, de novo sequencing is the only way to get valuable peptide sequence information. In a process called de novo sequencing, peptide sequences are derived from the masses of their fragments as shown on a tandem mass spectrum. When performing de novo sequencing, no protein sequence database is used for reference. One of the cores PEAKS technology is the fastest, most accurate auto de novo algorithm available on the market. Run auto de novo on an entire LC run, or a batch of them - process data faster than you can make it (40+ spectra per second). The results are unmatched in accuracy; PEAKS determines at least 3 times as many completely correct sequences as the next best de novo software. Accurate mass capabilities mean de novo at 97% accuracy is possible. With its easy to use, easy to read graphical user interface, PEAKS shows reliable and easy to read confidence scores. Confidence is not only on the peptide sequence, but on each amino acid assignment. PEAKS is the only software to provide confidence assignment at the amino acid level. Researchers can find the most pertinent information at a glance. Yet, all the information needed for in depth analysis is provided, without cluttering up the display. PEAKS can find post-translational modifications on peptides when de novo sequencing, and position them in the sequence. PEAKS is the only de novo sequencing software specifically tuned to handle data from QTOF, TOF-TOF, Ion Trap, Orbi-Trap and FTMS instruments, while using y and b ions or c and z ions for fragmentation flexibility. It provides a reliable central processing tool for all instrument and experiment types. It is comfortable in any dynamic core facility or demanding private research group. But PEAKS doesn't stop at auto de novo. In addition to automatic de novo sequencing, PEAKS' comprehensive set of assisted manual sequencing tools allow users to edit the results from a PEAKS processed spectrum. But most importantly, PEAKS has an integrated database search for protein identification tool -- a unique approach to protein ID that uses de novo sequencing to help in the search. Next Page => Learn about the next generation hybrid and meta-search protein ID tools.