PEAKS Protein Identification

PEAKS knows accurate protein identification is accomplished by more than protein database searching alone. That said, a reliable search engine is a crucial step in protein identification. PEAKS has proven itself in benchmark test against many other popular proteomic database search engines on high mass accuracy data, with high accuracy.

Using mass spectrometry, masses of peptides or fragments of peptides can be compared against the theoretical masses of the protein subsequences to identify the peptides. By inference, proteins can be identified in this manner. Traditional database search tools designed for this purpose struggle with the balance between false positive peptide assignments and low sensitivity.

Click image to view full scale Protein Identification window

The Ultimate Protein Identification

The PEAKS inChorus meta protein identification search tool allows for multiple proteomic search engines to combine their results for greater coverage and confidence. The most powerful solution involves a hybrid search approach like PEAKS and a more traditional tool for the best coverage. As hard as our competitors and us have tried, top researchers still admit that no single protein identification search engine yields perfect results. This is why all researchers are encouraged to use two or more protein identification tools to validate results and increase coverage.

PEAKS inChorus gives you the ability to use 5 search engines at once!

PEAKS Protein Identification
X!Tandem
OMSSA
Mascot
Sequest

Not wanting users to be limited, PEAKS bundles in three unique search engines, X!Tandem, OMSSA and PEAKS protein identification, at no additional cost, in addition to allowing Mascot and Sequest to be connected seamlessly. That's correct, PEAKS inChorus can launch and load third party search engines, as well as perform all its other tasks. Providing the ultimate protein identification solution is just one of the many features that makes PEAKS a prefered mass spectrometry software.

Clear, Concise Reporting

PEAKS shows reliable and easy to read confidence scores. Users can find the most pertinent information at a glance. Yet, all the information needed for in depth analysis is provided, without cluttering up the display.

PEAKS supports data from all major instrument vendors as well as most standard mass spectrometry data formats. It provides a reliable central processing tool for all instrument types.

Since proteins are often modified after translation, the identification of post-translational modifications (PTM), is an essential function of any protein identification tool. PEAKS provides the most flexible handling of post-translational modifications. Users are free to search for any number of PTM at once. Modifications can be selected from a pre-defined list, edited, or created from scratch. The position of a PTM is displayed in sequence, and confidence scores assigned.

Next Page => Learn more about PEAKS inChorus (meta protein identification).