Peptide ID with Multiple Engines
If you have access to another database search engine, then the inChorus function of PEAKS can make use of it by combining the database search results of PEAKS DB and with the other search engines.The combination of multiple engines will not only increase the coverage, but also the confidence since the engines using independent algorithms and therefore confirm each others results (Figure 1). In fact, PEAKS inChorus can directly invoke many of the supported engines and display all results in a united graphical user interface. This saves the tedious manual work of running different engines and loading their results separately.
Multiple Engine Proteomics Search Workflow
Multiple engine proteomics search results are displayed in a unified interface (Figure 2), with the engine icons indicating which engine or engines identified the same peptide-spectrum match (PSM). A blue background indicates that the engine assigned a higher-than-threshold score to the corresponding PSM and a white background indicates the score is lower than threshold from that engine.