We’re excited to unveil ProteoformX™, a next-generation software platform built to make intact and top-down proteomics more accessible, insightful, and powerful than ever before.
Proteins don’t operate as single, uniform molecules. Instead, they exist as proteoforms—unique molecular versions shaped by genetic variation, alternative splicing, and post-translational modifications (PTMs). These proteoforms define biological function, and ProteoformX™ is here to help you explore them in unprecedented detail.
Key Capabilities of ProteoformX™
Intact Mass Analysis with High Precision
ProteoformX™ uses feature-based deconvolution to identify proteoform masses with high sensitivity across a range of data types, whether isotopically resolved or not. It handles complex and heterogeneous samples with ease, including glycoforms and antibody-drug conjugates.
Top-Down Proteome Search
Dive deep into proteoform structure and modification mapping using diverse fragmentation methods like CID, ETD, HCD, UVPD, and more. The intuitive interface walks users from raw spectra to confident identifications.
Proteoform Manager for Custom Modelling
Define linkages, PTMs, glycosylation sites, and cleavage points using the Proteoform Manager’s flexible visualization tools. Perfect for biopharmaceutical workflows and advanced protein characterization.
Interactive Results and Visualisation
From hierarchical protein-to-proteoform tracking to fully annotated spectra, ProteoformX™ gives users complete control and clarity over their results. Explore interactive MS1 and MS2 views, identify isolation window overlaps, and analyse chimera spectra with color-coded precision.
Open Search for Expanded Insight
Enable OpenPTM Search to detect unexpected modifications and truncations. This opens the door to more complete proteoform identification, revealing biological changes that standard searches often miss.
Get Started with ProteoformX™ Today
Explore the power of intact and top-down proteomics like never before. Visit our product page to learn more.
The PEAKS Team
Bioinformatics Solutions Inc.