CPEB1 directs muscle stem cell activation by reprogramming the translational landscape

Understanding what causes a stem cell to enter the cell cycle, and what happens when it does, is key to determining how we can maximise the therapeutic potential of these cells to repair injured tissues or treat diseases. Here, Zeng et al., use LC-MS/MS to study the activation of a particular type of stem cell, Satellite cells (SC), that have the potential to repair damaged skeletal muscle.