A recent paper in Nature, from the Church Lab at Harvard Medical School and the Wyss Institute introduces AGENTEX (automated genetic tRNA expansion), a robotic, multiplexed tool for building and testing new genetic codes in cell-free translation systems.
Mistranslation from an endogenous tRNA variant in human pan-genome cell lines
Recent paper highlights that naturally occurring human tRNA variants can drive high levels of systematic mistranslation in healthy cells.
Deep coverage and extended sequence reads obtained with a single archaeal protease expedite de novo protein sequencing by mass spectrometry
Advancing de novo antibody sequencing with hyperthermal proteases and next‑gen fragmentation.
Scanning DIA on the ZenoTOF 8600 system enables ultra-sensitive and quantitative proteomics from single cells to post-translational modifications in a compact platform
PEAKS Studio 13.1 shows off its application prowess in working with the new ZenoTOF 8600!
Polyclonal Antibody Therapeutics: Analytical Innovations and Regulatory Perspectives for Addressing Heterogeneity Challenges
AI is reshaping how we characterise complex antibody therapeutics—and PolySeq.AI is part of that conversation! We’re excited to see PolySeq.AI,...
The Antitumor Activities of Anti-CD47 Antibodies Require Fc-FcγR interactions
Osorio, J. C., Smith, P., Knorr, D. A., & Ravetch, J. V. (2023). The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions. Cancer Cell, 41(12). doi:10.1016/j.ccell.2023.10.007
Identification Of Proteins with Variable Levels of Post-Translational Modifications in Human Temporal Lobe Epilepsy
Miroshnichenko et al. harnessed the power of PEAKS Studio to uncover differences in protein PTM levels.
MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens
A new study in Cell Reports Methods by Cell Press takes immunopeptidomics in an exciting new direction.
The proteome of the late Middle Pleistocene Harbin individual
Fu, Q., Bai, F., Rao, H., Chen, S., Ji, Y., Liu, A., et al. (2025). The proteome of the late Middle Pleistocene Harbin individual. Science. https://doi.org/10.1126/science.adu9677
Rapid and direct discovery of functional tumor specific neoantigens by high resolution mass spectrometry and novel algorithm prediction
Tian, H., Li, G., Chiu, C. K., Li, E., Chen, Y., Zhu, T., ... & Kang, X. (2025). Rapid and direct discovery of functional tumor specific neoantigens by high resolution mass spectrometry and novel algorithm prediction. Cell Insight, 100251. doi:10.1016/j.cellin.2025.100251