Glioblastoma (GBM) is the most common and malignant brain tumour. Learn how LC-MS/MS is proving to be a beneficial method to understanding of brain extracellular matrix changes in GBM pathogenesis and discovery of novel makers and therapeutic targets.
Alterations in the matrisome, including collagens, glycoproteins, and proteoglycans, have been shown to be associated with neurodegenerative disorders. Here researchers investigated the alterations in the expression and modification of the matrisome.
PEAKS Online provides a high-throughput analysis of large-scale DDA and DIA datasets. This platform integrates spectral library search, database search, and de novo sequencing that employs deep learning-based technology to increase the sensitivity and accuracy of peptide identification.
Though there appears to be both genetic and environmental factors that influence the development of Myopia or nearsightedness, the precise mechanism remains unknown. In this study the research group aimed to analyze the exosomal protein profile of the aqueous humor (AH) of myopia patients to provide insight for the diagnosis, clinical treatment and prognosis of myopia.