PEAKS GlycanFinder 3.0 is Here
Smarter Workflows, Deeper Discovery
We are proud to introduce PEAKS GlycanFinder 3.0, the latest evolution of our glycoproteomics and glycomics software platform. This release brings powerful new features and workflow improvements to take your research to the next level.
1. Glycan Modification Support
Glycans' structural diversity is further expanded by natural modifications such as phosphorylation and sulfation, which influence biological activity and can serve as disease biomarkers. In GlycanFinder 3.0, glycan modifications are supported in both glycopeptide and released glycan workflows.
2. Improved Sensitivity for EAD/EAciD
In GlycanFinder 3.0, glycopeptide identification using EAD fragmentation is significantly improved. Enhanced scoring for EAD and EAciD fragmentation increases identification sensitivity.
3. InChorus - Cross-engine Consensus Result
In glycoproteomics, glycopeptide identifications often vary across search engines, leading to inconsistent or ambiguous annotations. GlycanFinder 3.0 addresses this challenge with its powerful new InChorus feature. InChorus integrates results from multiple search engines for glycopeptides, highlighting both consensus and unique glycopeptide findings in a user-friendly display. This unbiased tool automatically extracts data from external search engines, visualises spectrum-level overlaps for each PSM, and provides intuitive filtering and export options–empowering users to validate results with enhanced confidence and clarity.
4. Improved Structural Resolution
Identified GPSMs are assigned a structural confidence level that integrates both peptide and glycan identification quality. Users can flexibly filter and select glycopeptides based on these confidence levels.
Glycan database search now allows for O-linked glycan search with up to 5 O-linked glycans per peptide, providing accurate identification and site determination.
The newly added paired spectra acquisition method (HCD-pd-EThcD) helps confidently assign both glycan structures and glycosylation sites. Additionally, GlycanFinder 3.0 supports paired spectra display for easy interpretation.
Ready to see what’s possible with PEAKS GlycanFinder 3.0?
Check out the full list of features and enhancements on our launch page.
Discover faster insights, deeper results, and more flexibility than ever before.
The PEAKS Team
Bioinformatics Solutions Inc.