Alterations in the proteomic composition of Serratia marcescens in response to manganese (II)

Queiroz et al. Deep learning enables de novo peptide sequencing from data-independent-acquisition mass spectrometry. BMC Biotechnology. 18(1), 83. 29/12/2018.

Proteomics is an important tool for the investigation of dynamic physiological responses of microbes under heavy metal stress. To gain insight into how bacteria respond to manganese (II) and identify the proteins involved in Mn (II) oxidation, the shotgun proteomics approach was applied to a potential Mn (II)-oxidizing Serratia marcescens strain cultivated in the absence and presence of Mn (II).