The effect of steam cooking on the proteolysis of pacific oyster (Crassostrea gigas) proteins: Digestibility, allergenicity, and bioactivity

The Pacific oyster is a major seafood around the world and it is important to understand the effect of heating on proteins of this aquatic species. Learn how LC-MS/MS was used and how studies on food processing can improve the safety of food and reduce health-related costs.

Cyclic immonium ion of lactyllysine reveals widespread lactylation in the human proteome

Lactylation is a post translation modification (PTM) derived from lactate and here, researchers have shown that lactylation is a widespread PTM that is not restricted to histones and have developed a sensitive and validated method for lactylation identification by liquid chromatography–tandem mass spectrometry (LC–MS/MS).

Proteomic analysis of Exosomes derived from the Aqueous Humor of Myopia Patients

Though there appears to be both genetic and environmental factors that influence the development of Myopia or nearsightedness, the precise mechanism remains unknown. In this study the research group aimed to analyze the exosomal protein profile of the aqueous humor (AH) of myopia patients to provide insight for the diagnosis, clinical treatment and prognosis of myopia.

A Novel Angiotensin-I-Converting Enzyme (ACE) Inhibitory Peptide from Takifugu flavidus

High blood pressure is a common chronic medical condition and a major risk factor in developing cardiovascular disease. The angiotensin-I-converting enzyme (ACE) plays a critical role in controlling blood pressure, and ACE inhibitors are a class of medication in use to treat high blood pressure. Learn how Su et al., studied marine organisms, Takifugu flavidus, to reveal a novel ACE inhibitory peptide.

CPEB1 directs muscle stem cell activation by reprogramming the translational landscape

Understanding what causes a stem cell to enter the cell cycle, and what happens when it does, is key to determining how we can maximise the therapeutic potential of these cells to repair injured tissues or treat diseases. Here, Zeng et al., use LC-MS/MS to study the activation of a particular type of stem cell, Satellite cells (SC), that have the potential to repair damaged skeletal muscle.